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[博士论坛]:2013年中国糖尿病和糖尿病前期流行病学和种族特征

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yangrui91 发表于 2017-11-19 20:42:19 | 显示全部楼层 |阅读模式
本帖最后由 yangrui91 于 2017-11-19 20:46 编辑

Prevalence and Ethnic Pattern of Diabetes and Prediabetes inChina in 2013.
2013年中国糖尿病和糖尿病前期流行病学和种族特征
作者:[url=]Wang L[/url] , [url=]Gao P[/url] , [url=]Zhang M[/url] ,et al.
期刊名称:The Journal of American Medical Association
发表时间:2017-6-27
JAMA. 2017 Jun 27;317(24):2515-2523.


Previous studies have shown increasing prevalence of diabetes in China, whichnow has the world's largest diabetes epidemic.
此前的研究显示,中国糖尿病患病率不断上升。目前,中国已成为世界上最大的糖尿病流行国家。


To estimate the recent prevalence andto investigate the ethnic variation of diabetes and prediabetes in the Chineseadult population. A nationally representative cross-sectional survey in 2013 inmainland China, which consisted of 170 287 participants.
为更好地估计中国糖尿病最新的患病率,并调查中国成年人糖尿病和糖尿病前期的种族差异,中国于2013年在全国进行了一项具有代表性的代表性横断面调查,共调查了17287名参与者。


Fasting plasma glucose and hemoglobinA1c levels were measured for all participants. A 2-hour oral glucose tolerancetest was conducted for all participants without diagnosed diabetes.
所有参与者均测量空腹血糖和糖化血红蛋白。对未诊断糖尿病的人群进行OGTT2,测2小时血糖。


Primary outcomes were total diabetesand prediabetes defined according to the 2010 American Diabetes Associationcriteria.
总体糖尿病和糖尿病前期的初步诊断标准,采用2010年美国糖尿病学会的诊断标准。


Awareness and treatment were alsoevaluated. Hemoglobin A1c concentration of less than 7.0% among treateddiabetes patients was considered adequate glycemic control. Minority ethnicgroups in China with at least 1000 participants (Tibetan, Zhuang, Manchu,Uyghur, and Muslim) were compared with Han participants.
我们还对知晓和治疗进行了评估。在治疗糖尿病患者中,糖化血红蛋白浓度低于7.0%,被认为是适当的血糖控制。与汉族相比,中国的少数民族至少有1000人(藏族、壮族、满族、回族和穆斯林)。


Among the Chinese adult population, theestimated standardized prevalence of total diagnosed and undiagnosed diabeteswas 10.9% (95% CI, 10.4%-11.5%);and that of prediabetes, 35.7% (95% CI,34.1%-37.4%).
在中国成年人中,标准化之后的确诊和未确诊糖尿病的患病率为10.9%(95%CI ,10.4%-11.5%);糖尿病前期患病率为35.7%(95%CI,34.1%-37.4%)。


Among persons with diabetes, 36.5% (95%CI, 34.3%-38.6%) were aware of their diagnosis and 32.2% (95% CI, 30.1%-34.2%)were treated; 49.2% (95% CI, 46.9%-51.5%) of patients treated had adequateglycemic control.
在糖尿病患者中,36.5%(95%CI,34.3%-38.6%)知道到他们的诊断,32.2%(95%CI,30.1%-34.2%)接受治疗;
49.2%(95%的CI,46.9%-51.5%)的患者有足够的血糖控制。


Tibetan and Muslim Chinese hadsignificantly lower crude prevalence of diabetes than Han participants (14.7%[95% CI, 14.6%-14.9%] for Han, 4.3% [95% CI, 3.5%-5.0%] for Tibetan, and 10.6%[95% CI, 9.3%-11.9%] for Muslim; P < .001 for Tibetan and Muslim comparedwith Han).
藏族和穆斯林族中国人的糖尿病患病率明显低于汉族(汉族14.7%,藏族4.3%,穆斯林族10.6%,藏族和穆斯林族的患病率显著低于汉族P <001。)。


In the multivariable logistic models,the adjusted odds ratios compared with Han participants were 0.42 (95% CI,0.35-0.50) for diabetes and 0.77 (95% CI, 0.71-0.84) for prediabetes forTibetan Chinese and 0.73 (95% CI, 0.63-0.85) for diabetes and 0.78 (95% CI,0.71-0.86) for prediabetes in Muslim Chinese.
在多元回归模型中,与汉族相比,藏族糖尿病人群为0.42,糖尿病前期为 0.77;与汉族相比,穆斯林族糖尿病人群为0.73,糖尿病前期为0.78。


Among adults in China, the estimatedoverall prevalence of diabetes was 10.9%, and that for prediabetes was 35.7%.Differences from previous estimates for 2010 may be due to an alternate methodof measuring hemoglobin A1c.
在中国的成年人中,糖尿病的总体患病率为10.9%,而糖尿病前期的患病率为35.7%。与2010年的评估不同,可能是由于糖化血红蛋白的测量方法不同所致。

2017博士一教班,杨锐,11700017

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